Integrative rodent models for assessing male reproductive toxicity of environmental endocrine active substances

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Integrative rodent models for assessing male reproductive toxicity of environmental endocrine active substances

In the present review, we first summarize the main benefits, limitations and pitfalls of conventional in vivo approaches to assessing male reproductive structures and functions in rodents in cases of endocrine active substance (EAS) exposure from the postulate that they may provide data that can be extrapolated to humans. Then, we briefly present some integrated approaches in rodents we have re...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2014

ISSN: 1008-682X

DOI: 10.4103/1008-682x.122366